University of Freiburg
Georges-Köhler-Allee 201
79110 Freiburg i. Br.
Germany
+49 (0)761 203-98637
philippe.coulon@biologie.uni-freiburg.de
coulon@uni-muenster.de
How do neuronal networks switch between states of activity in health and disease? The biological mechanisms that are fundamental to movement, naturally occurring sleep, attention, pain signalling, or the conscious awareness of our environment in the brain’s largest network, the thalamocortical system, can also be the cause for epilepsy, Parkinsonism, or autism spectrum disorders. Understanding these mechanisms is a crucial step to understanding the organisation, function, and dysfunction of the brain.
| since 2018 | Venia legendi in Neurobiology, University Freiburg, Faculty of Biology (Privatdozent, Dr. rer. nat. habil.) |
| 2017 - today | Optophysiology lab - Prof. Diester. Albert-Ludwigs-University Freiburg, Germany, Senior Research Scientist |
| 2015 - 2016 | Center for Integrative Brain Research, Seattle Children’s Research Institute, Seattle, WA, USA, Fellow PhD |
| 2014 | Epilepsy Research Center Münster and Institute of Anatomy and Molecular Neurobiology, University Münster |
| 10/2013 | Habilitation. Venia legendi in Physiology, Privatdozent, University Münster, Medical Faculty |
| 2006 - 2013 | Institute of Physiology I, Münster (PostDoc 2006-2010, Senior PostDoc 2011-2012, Principal Investigator @ IMF Münster 2012-2013) |
| 2005 | Coordinator of the International Graduate School of Neuroscience (IGSN), Bochum |
| 01/2005 | Graduation as Dr. rer. nat. (PhD), Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany |
| 2000 - 2005 | Research Associate, Institute of Neurobiology, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Germany |
| 11/2001 | Dipl.-Biol. (MSc Biology) |
| 1994 - 2000 | Studied Biology, Dipl.-Biol. (MSc), Heinrich Heine University Düsseldorf, Germany |
Jaeckel Z, Adzemovic A, Kloos B, Hardung S, Sanchez-Brandelik R, Coulon P, Diester I (2024) A Retrospective Report of Carprofen Administration as Post-Operative Analgesia Reveals Negative Effects of Recommended Doses. Animals. 14, 3157. doi:https://doi.org/10.3390/ani14213157.
Coulon P (2021) Electrophysiological and Calcium Imaging Approaches to Study Metabotropic Glutamate Receptors. In: Olive M.F., Burrows B.T., Leyrer-Jackson J.M. (eds) Metabotropic Glutamate Receptor Technologies. Neuromethods. Vol 164. Humana, New York, NY. doi 10.1007/978-1-0716-1107-4.
De La Crompe B, Coulon P, Diester I (2020) Functional interrogation of neural circuits with virally transmitted optogenetic tools. Journal of Neuroscience Methods.57:157-163. doi: 10.1016/j.sbi.2019.04.003.
Eriksson D, Schneck M, Schneider A, Coulon P, Diester I (2020) A starting kit for training and establishing in vivo electrophysiology, intracranial pharmacology, and optogenetics. J Neurosci Methods. 336:108636. doi: 10.1016/j.jneumeth.2020.108636.
Deubner J, Coulon P, Diester I (2019) Optogenetic approaches to study the mammalian brain. Curr Opin Struct Biol. 57:157-163. doi: 10.1016/j.sbi.2019.04.003.
Coulon P, Landisman CE (2017) The Potential Role of Gap Junctional Plasticity in the Regulation of State. Neuron. 93(6):1275-1295. doi: 10.1016/j.neuron.2017.02.041.
Kohmann D, Lüttjohann A, Seidenbecher T, Coulon P, Pape HC (2016) Short-term depression of gap junctional coupling in reticular thalamic neurons of absence epileptic rats. J Physiol. 594(19):5695-710. doi: 10.1113/JP271811.
Coulon P, Gorji A. Tightrope or Slackline? The Neuroscience of Psychoactive Substances (2016) Trends Pharmacol Sci. 37(7):511-521. doi: 10.1016/j.tips.2016.04.004.
Neyer C, Herr D, Kohmann D, Budde T, Pape HC, Coulon P (2016) mGluR-mediated calcium signalling in the thalamic reticular nucleus. Cell Calcium. 59(6):312-23. doi: 10.1016/j.ceca.2016.03.009.
Cerina M, Szkudlarek HJ, Coulon P, Meuth P, Kanyshkova T, Nguyen XV, Göbel K, Seidenbecher T, Meuth SG, Pape HC, Budde T (2015) Thalamic Kv 7 channels: pharmacological properties and activity control during noxious signal processing. Br J Pharmacol. 172(12):3126-40. doi: 10.1111/bph.13113.