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Merry Christmas

During our festive Christmas celebration, we reflected on an exciting year of scientific discoveries. The evening was filled with punch, nice food, stories, and papersongs. Live music was, of course, a must-have addition to the party.
The Optophysiology Lab wishes you a Merry Christmas and a good start to the year 2025.

New Article Published in Animals

Ensuring proper pain relief in laboratory animals is vital for their welfare and for obtaining accurate scientific results. We retrospectively examined the effects of carprofen as post-operative analgesia in Sprague Dawley rats following stereotactic surgery.

New Article Published in bioRxiv

In this study, we employed an action-preparation task in rats, combined with bidirectional optogenetic interventions, opto-fMRI, single unit electrophysiology and local field potential synchrony measurements across PFC subsections. Our findings support a clear and simple model of action inhibition within the prefrontal network.

New Article Published in Transactions on Machine Learning Research

In this paper we propose the novel class of hierarchical inverse Q-learning (HIQL) algorithms, which extend the fixed-reward inverse Q-learning (IQL) framework from Kalweit et al. (2020) to solve multiintention IRL problems. We applied HIQL in a real mice decision-making dataset from a dynamic two-armed bandit task (De La Crompe et al., 2023), and mathematically characterized exploitation and exploration behavior of animals during value-based decision-making.

New Article Published in Neuron

How do brains—biological or artificial—respond and adapt to an ever-changing environment? In a recent meeting, experts from various fields of neuroscience and artificial intelligence met to discuss internal world models in brains and machines, arguing for an interdisciplinary approach to gain deeper insights into the underlying mechanisms.

June 21, 2024: Farewell Party

Dear Brice, it was a pleasure working with you. Thank you for your time and dedication while you worked in our team. All the best for your next step.
“Brice, Brice, au revoir”

February 9, 2024: Are Clownfish able to Count?

Clownfish can apparently count – this is the conclusion drawn by Japanese researchers from an experiment they conducted on the territorial behavior of the animals. Is this really true? “The researchers are jumping to conclusions,” says Prof. Dr. Ilka Diester.

New Article Published in arXiv

In this study, we introduce a novel class of Latent (Markov) Variable Inverse Q-learning algorithms for characterizing animal behavior during complex decision-making tasks.

New Article Published in eNeuro

To study behavioral flexibility in freely-moving mice, we developed a versatile, low-cost, open-source behavioral setup, called FreiBox, allowing us to investigate the neuronal correlates of licking-based behavioral flexibility.

New Article Published in Neuron

This study proposes an unitary concept that, leveraging a cross-species definition of prefrontal regions, explains how prefrontal ensembles adaptively regulate and efficiently coordinate multiple processes in distinct cognitive behaviors.

New Article Published in bioRxiv

This study provides mechanistic insights into the interactions between the rostral forelimb area (RFA) and the caudal forelimb area (CFA). Specifically, we provide evidence for a differential impact of RFA on CFA depending on the task phase and the targeted CFA layers.

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